Abstract

Sateesh Gound*, Jai Narayan Mishra, Ashutosh Kushwaha and Priyanka Maurya

ABSTRACT

The novel drug delivery vehicle, liposomes has been established themselves as a promising in the several different basic science and as a viable alternative in several, different applications. Liposomes were the small microscopic spheres with an aqueous core surrounded by one or more outer shells that consisting of lipids were arranged in the bilayers configuration. They will be acceptable superior carriers having ability to encapsulated hydrophilic and lipophilic drugs and protected them from degradation. Liposomes applied on the skin as well as local depot at the same time diminishing the sides effects of these drugs, they act as a solubilizing matrix for poorly soluble drugs and penetration enhancers. They give better absorption from its their has been also affinity to keratin of horny layer of skin and can penetrate deeper into skin. Topical Liposomes formulation could be less toxic and more effective than conventional formulations. The liposomal gel formulations that perform therapeutically better effects than the other conventional formulations, as prolonged and controlled released the topical dosage forms, may also leads to the improved efficiency and better patients compliance.