Abstract

Chaithra Shaji*, Dr. C. Jose Gnana Babu, Dr. D. Visagaperumal and Dr. Vineeth Chandy

ABSTRACT

Ayapana triplinervis also known as Ayapana, is a medicinal plant widely used in healing processes and in mystical-religious rituals by traditional communities in South America, Africa, and Asia. It is a perennial shrub native to the Amazon rainforests of South America. Ayapana has three different Latin names (Ayapana triplinervis, Eupatorium ayapana, and Eupatorium triplinerve), but all three names refer to the same plant. The flowers are pale pink, and the stem is reddish, hairless and thin. Traditional medicinal practices have long utilized various parts of the plant for treating a wide range of ailments, including digestive disorders, respiratory ailments and skin conditions. Chemical constituents like 7-ethoxy coumarin (ayapanin), 6,7-dimethoxy coumarin (ayapin), hydrangetin, daphnetin, daphnetin dimethyl ether, 7-methyl daphnetin ether, umbelliferone, carotene, vitamin C and stigmasterol have been isolated from the plant. Furthermore, recent scientific investigations have highlighted the therapeutic potential of Ayapana triplinervis in the management of various health conditions such as antioxidant, antimicrobial, anti-inflammatory, antitumorous, hepatoprotective, antiulcerous, gastroprotective and antinociceptive activity. This review aims to provide a comprehensive overview of Ayapana triplinervis, covering its botanical characteristics, phytochemical composition and pharmacological activities. Overall, Ayapana triplinervis emerges as a valuable botanical resource with significant therapeutic potential, deserving further exploration for its diverse health benefits.