Abstract

P. Karnan*, A. Anbarasu and Dr. R. Usha

ABSTRACT

In the beginning period of Oncological research cancer is the challengeable one among the people particularly breast cancer has been form due to poor self hygienic and social hygienic status. But this review to explain the structural changes in mitochondria in breast cancer cells and role of vitamin-D. The characterisation of the cyto morphological features in the malignant stages may infer the molecular level changes that have taken place inside the cancer cells which in turn have a bearing on better patient management. The clear understanding of breast cancer and identification of some cardinal changes in the ultra structure of organelles like mitochondria will provide more insights and possibilities about the oxidative status and oxidative stress. The histological findings beforehand will enable various precautionary measures to be taken to avoid the risk factors in general by all women and very particularly by the familial group individuals who inherit the pedigree relationships. The study reported the structural abnormalities in the mitochondria of breast cancer tissue cells and collates the above changes with other causation agent’s viz., vitamin –D.