Abstract

Deeksha Tiwari*, Surbhi Chourasia, Ravish Kumar Sahu, Ajay Singh Thakur, Ramdarshan Parashar, Yogesh Sharma and Deepak Koshti

ABSTRACT

Dandruff is a shedding of dead skin cells from the scalp and is suffered by almost50% of the population and causes significant discomfort. The severity can rangefrom mild scaling to dry skin to severe scaling. Malassezia furfur is considered tobe the cause of dandruff. Dandruff may also be caused by changes in humidity,trauma, seasonal changes or emotional stress. The present research has beenundertaken with the aim to formulate and evaluate the herbal gelcontaining Emblica officinalis. Gaertn, Citrus limonum. Risso, Allium sativum.Linn, and Zingiber officinale. Eight batches (F1, F2, F3 F4, F5, F6, F7 and F8) ofHerbal Antidandruff gel were formulated. The gel formulation was designed byusing aqueous, aqueous extracts in varied concentrations along with differentpolymer. The physiochemical parameters of formulations (pH, viscosity,spreadability etc.) were determined. The results showed the stability study wereperformed for the selected formulation (F8) by both the technique as per the ICHguidelines. The gel was subjected to stability study at 40oC±2oC and 75±5% RH,samples were withdrawn on 1 month, 2 month, 3 month and analysed. The resultshown that the product is stable for 3 months without change in physical changes.Since the antimicrobial studies has given encouraging results in enhancing theantidandruff activity of F8 formulation, it is concluded that the F8 Herbalantidandruff gel may be subjected to further in-vivo and clinical trials.