Abstract

*Dr. Divya Kadali, Annem Venkata Shalmija, Dr. Appari Sonia, Dr. Reehana Pathan, Dr. Vaishnavi Bhattiprolu, Dr. Sri Ramya Komera and Dr. Devika Kolasani

ABSTRACT

Aim: The metabolic effect of estrogen and progesterone levels on bone tissue is ofconcern in the placement of endosseous dental implants. This study was undertakento evaluate and compare the amount of bone remodelling around implants inpatients with high endogenous serum estrogen and patients with low endogenousserum estrogen by assessing the levels of serum alkaline phosphatase, serum acidphosphatase, and serum calcium levels, which are biochemical products used asmarkers of bone remodelling. Materials and Methods: 20 females and 10 malecontrols were included in the study. In 10 females, implants were placed 10 daysafter menstruation (high estrogen group) and in 10 females, implants were placedduring menses (low estrogen group). Clinical parameters like estrogen,progesterone, alkaline phosphatase and acid phosphatase in the serum wererecorded at baseline and after 9 months. Results: Laboratory values of estrogen,progesterone, alkaline phosphatase and acid phosphatase in the serum varied greatlyby individual. The alkaline phosphatase levels were significantly higher in the highestrogen female group and the acid phosphatase levels were higher in the lowestrogen female group. Conclusion: The clinical success of dental implantintegration was seen regardless of the temporal physiological fluctuations in theovulatory cycle. There were no differences observed within the confines of thestudy in the bone remodelling around dental implants. Since it is obvious that thetemporary hormonal fluctuation is not the sole factor responsible for the complexprocess of bone metabolism and bone healing, the dental implant osseointegrationwas not influenced by the temporary fluctuations in the ovulatory cycle. Hence,within the limitations of this study, bone remodelling around dental implants wasnot influenced by sex hormones.