SOLID LIPID NANOPARTICLES AS A NOVEL DRUG DELIVERY SYSTEM: A COMPREHENSIVE REVIEW
Netrapal Singh* and Dr. Gurpreet Singh
ABSTRACT
Alternative drug delivery methods to colloidal carriers including liposomes, emulsions, and polymeric micro- and nanoparticles include solid lipid nanoparticles (SLNs). One of the most cutting-edge methods for addressing drug delivery's targeting and bioavailability problems is the use of SLNs. This review covers every important aspect of SLNs, including their manufacturing processes, various SLN models, drug incorporation, loading capacity, and drug release, as well as the most recent characterization techniques, their uses, and developments in the delivery of biological drugs, such as gene vectors, novel adjuvants for vaccines, proteins, and peptides with SLNs. According to the data that is now available, SLNs have a wider chance of success in the future since they can be readily created with a variety of features that have a huge potential for targeting and diagnosing a wide range of disorders. With the current conversation that reframes the potential of SLNs and compiles the various research findings of SLNs in tabular form along with the approved patent technologies of SLNs, this review will assist aspiring researchers in learning about the unexplored areas of SLNs.
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