A DETAILED REVIEW ON THE ROLE OF EXCIPIENTS IN PHARMACEUTICAL FORMULATIONS
Rupesh Ishwar Nathbuva*, Adarsh Pravin Gawande, Jayesh Ashok Chaudhari, Mayur Milind Patil, Ekesh Manohar Mahajan
ABSTRACT
Excipients play important role in formulating dosage form. These are ingredients added with various active pharmaceutical ingredients make up the dosage form. Pharmaceutical excipients having the backbone of an Pharmaceutical formulations. Excipients act as protective, as a bulking agent and increase bioavailability of Drugs. In this review we discuss about the sources of various types of excipients they occur along with uses, their selection criteria and various interaction that an excipients during it course stay in formulations has be discussed in this review. Some excipients interaction can be toxic and need to be avoided. The following review gives brief information about the stability study , drug excipients compatibility and along with their various safety evaluation parameters of the excipients.
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