Abstract

P. Akhila*, K. Vedith Reddy, S. Veena, K. Harshitha and Dr. K. T. Naik

ABSTRACT

Antimicrobial resistance (AMR) is a pressing global health crisis fueled by themisuse and overuse of antibiotics across healthcare, agriculture, and animalhusbandry. Since the discovery of penicillin, the rise of multidrug-resistantpathogens has posed severe challenges to healthcare systems worldwide.Mismanagement of antibiotics in human and veterinary medicine, along withagricultural practices, accelerates the spread of resistance genes, creating a "SilentPandemic" predicted to surpass other leading causes of mortality by 2050.Emerging technologies, including artificial intelligence, offer promising tools tocombat AMR by enhancing diagnostics and optimizing treatment strategies.However, challenges such as data quality and algorithmic biases must be addressedto fully realize their potential. Key strategies include strengthening surveillancesystems, implementing antimicrobial stewardship programs, and investing in theresearch and development of novel antimicrobials. Raising public awareness,improving education, and fostering international collaboration are vital topreserving the efficacy of antibiotics and safeguarding public health for futuregenerations. Addressing AMR requires urgent, coordinated efforts to mitigate itsescalating threat and ensure sustainable global health outcomes. This reviewhighlights the urgent need for equitable access to resources, enhanced globalcollaboration, and sustained investments to mitigate the AMR crisis. Byimplementing these strategies, the global community can safeguard theeffectiveness of antimicrobials and protect public health against the escalatingthreat of resistant infections.