Abstract

Xandra S. De Guzman*, Efren Tangon, Radzmina B. Bariwah, Zahra U. Mastul-Gani, Bel-adzri T. Bellio, John Mark S. Jacoba

ABSTRACT

Phytochemical screening of various marine species is essential for uncovering and recognizing varied potentials in pharmacognosy that may yield significant health benefits. The toxicity characteristics of the species will enhance subsequent investigations into diverse medicinal applications. This study aimed to determine the bioactive compounds in the brown macroalgae Padina australis from Pasiagan, Bongao, Tawi-Tawi and assess their toxicity. The results showed that Padina australis had a variety of active secondary metabolites, such as alkaloids, flavonoids, saponins, phenols, tannins, triterpenoids, and steroids, whereas, cardiac glycosides were not present. The toxicity test indicated a lethal concentration 50 (LC50) value of 1288.25 μg/ml, categorizing it as non-toxic. These results suggest that Padina australis from Pasiagan, Bongao, Tawi-Tawi, with its notable bioactive potential, could be beneficial for future pharmaceutical applications and may also have potential as food sustenance due to its low toxicity. Further research is recommended to explore the full spectrum of its medicinal and nutritional benefits.