Abstract

John Mark S. Jacoba*, Efren Tangon, Xandra S. De Guzman, Fatimah Raiza I. Abubakar, Ian Patrick S. Jaudinez and Indal Fitra S. Daham

ABSTRACT

Phytochemical screening is a rigorous scientific endeavor that involves the isolation and characterization of plant-derived bioactive compounds. Through a series of analytical techniques, researchers can identify and quantify these phytochemicals, paving the way for their potential application in various fields, including medicine, food science, and cosmetics. Plant toxicity results from the consumption of plant-derived substances that possess toxic properties. This study aimed to determine the phytochemicals effect and toxicity effects of Philodendron erubescene. Leaflets were collected from Batu-Batu, Panglima Sugala, Tawi-Tawi, and subjected to methanolic process. The results extract was screened for phytochemicals using various tests including Wagner’s test for alkaloids, ferric chloride test for phenolics and tannins test, and Salkowski test for triterpenoids. The extract was found to contain alkaloids, flavonoids, saponins phenolics, and tannins steroids. The toxicity of the extract was evaluated using the brine shrimp lethality assay. The results showed that the extract exhibited notable cytotoxic effects, with an LC50 value of 1.901 ppm. This finding underscores the potential toxicity of the extract and its implications for aquatic organisms. The study demonstrates the potential of Philodendron erubescens leaflets contains various phytochemicals and exhibits cytotoxic effects. These findings suggest that the tested plants exhibit potent cytotoxic activity, indicating their potential as natural sources of cytotoxic agents for local applications the findings are consistent with previous studies on the phytochemical composition and biological activities of Philodendron species.