PHYTOCHEMICAL SCREENING AND TOXICITY TEST OF IXORA COCCINEA OF SANGA-SANGA, BONGAO, TAWI-TAWI, PHILIPPINES
Fatimah Raiza I. Abubakar*, Efren Tangon, John Mark S. Jacoba and Indal Fitra S. Daham
ABSTRACT
Phytochemical screening of terrestrial plant extracts provides fundamental data on their medicinal properties, identifying potential lead compounds for pharmaceutical development and elucidating chemical composition. Variations in flower extracts and other applications were observed. Ixora coccinea's bioactive compounds were identified and evaluated for cytotoxicity, revealing potential medicinal applications. Phytochemical and proximate analyses were conducted on Ixora coccinea flowers using standard methods on a dry basis. The results revealed methanolic extracts possessed various active secondary metabolites, including alkaloids, flavonoids, glycosides, phenolics and tannins, along with notable bioactive potential advantageous for future pharmaceutical applications. Cytotoxicity tests indicated an LC50 value of 1519.51 ppm, suggesting non-toxic properties. These findings suggest Ixora coccinea may serve as a feed source, underscoring the importance of conserving and exploring Philippine plant species bioactive potential.
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