PHYTOCHEMICAL PROFILING AND BRINE SHRIMP LETHALITY TEST OF THE METHANOL EXTRACT OF LANTANA CAMARA FROM SIMUNUL, TAWI-TAWI, PHILIPPINES
Kris A. Langamin*, Mark Vincent B. Langamin, Efren Tangon, Jocelyn A. Pajiji and Fatimah Raiza I. Abubakar
ABSTRACT
Phytochemical screening of different terrestrial plant species is necessary in recognizing and characterizing bioactive compounds present in plant extracts that may yield significant benefits in medicinal applications. At the same time, toxicity will help evaluate the bioactivity of plant extracts which provides an understanding of the potential pharmacological activities of the species. This study examined the phytochemical profile and toxic potential of Lantana camara leaflet extract from Simunul, Tawi-Tawi. Phytochemical screening revealed the existence of alkaloids, cardiac glycosides, flavonoids, phenolics, saponins, steroids, tannins, and triterpenoids. Brine Shrimp Lethality Test (BSLT) displayed toxic properties, with LC50 values of 870.96 μg/ml. The result demonstrated concentration-dependent toxic effects, presenting potential pharmacological properties. These findings backed the conventional use of Lantana camara as it comprises a myriad array of active secondary metabolites with substantial bioactive potential that would be useful in developing and formulating new drugs or therapeutic agents that are valuable in the contribution of pharmacology advancements.
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