International Journal Of Modern
Pharmaceutical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Science & Pharmacy Professional

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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ISSN 2319-5878
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Abstract

PHYTOCHEMICAL PROFILING AND BRINE SHRIMP LETHALITY TEST OF THE METHANOL EXTRACT OF LANTANA CAMARA FROM SIMUNUL, TAWI-TAWI, PHILIPPINES

Kris A. Langamin*, Mark Vincent B. Langamin, Efren Tangon, Jocelyn A. Pajiji and Fatimah Raiza I. Abubakar

ABSTRACT

Phytochemical screening of different terrestrial plant species is necessary in recognizing and characterizing bioactive compounds present in plant extracts that may yield significant benefits in medicinal applications. At the same time, toxicity will help evaluate the bioactivity of plant extracts which provides an understanding of the potential pharmacological activities of the species. This study examined the phytochemical profile and toxic potential of Lantana camara leaflet extract from Simunul, Tawi-Tawi. Phytochemical screening revealed the existence of alkaloids, cardiac glycosides, flavonoids, phenolics, saponins, steroids, tannins, and triterpenoids. Brine Shrimp Lethality Test (BSLT) displayed toxic properties, with LC50 values of 870.96 μg/ml. The result demonstrated concentration-dependent toxic effects, presenting potential pharmacological properties. These findings backed the conventional use of Lantana camara as it comprises a myriad array of active secondary metabolites with substantial bioactive potential that would be useful in developing and formulating new drugs or therapeutic agents that are valuable in the contribution of pharmacology advancements.

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