Abstract

Srigadi Goutham Kumar*, Oruganti Kalyani, Ippuram Rishita, Burra Kavya, Gulla Sowmya, Aavunoori Prasanna Laxmi and Sankata Rajesh

ABSTRACT

Helminthic infections are among the most wide spread infection in humans thatcause severe morbidity. It is one of the most serious problems in the developingcountries. Traditional plant based remedies continue to be an important therapeuticaid for treating parasitic infections. As Gastrointestinal worms are hardy, currentlyavailable antihelmintic drugs and the high cost of conventional antihelmintics makemedicinal plants to be evaluated as alternative sources of antihelmintic drugs. Inthis study ethanol and ethyl acetate extracts of Averrhoa carambola leaves wereconducted to evaluate the potential antihelmintic effect of the extract. Antihelminticactivity against the earthworm Pheritima postuma was tested at concentrations of 10mg/ml, 20 mg/ml of both extracts. The results were expressed as paralysis time anddeath time of the worms. Ethanol at 20 mg/ml concentration showed betterantihelmintic activity compared to standard drug and other extract.