Abstract

Yash K. Chajed*, Shravan J. Somani and Dr. Mahesh R. Sherkar

ABSTRACT

Gulvel (Tephrosia purpurea), a traditional medicinal plant, has garnered significant attention for its potential therapeutic applications. This review paper delves into the antioxidant properties of Gulvel and its various constituents. Gulvel (commonly known as Tinospora cordifolia), a medicinal plant widely recognized in traditional Ayurvedic practices, has garnered increasing attention for its potential therapeutic properties, including its antioxidant activity. This review synthesizes existing research on the antioxidant properties of Gulvel, highlighting its bioactive compounds, mechanisms of action, and potential health benefits. Various studies have demonstrated that Gulvel's chemical constituents, such as alkaloids, flavonoids, and terpenoids, possess significant free radical-scavenging activity, contributing to cellular protection against oxidative stress. These antioxidants are believed to mitigate the damage caused by reactive oxygen species (ROS), which is implicated in the pathogenesis of numerous chronic diseases, including cancer, cardiovascular diseases, and neurodegenerative disorders. Furthermore, the plant’s ability to modulate antioxidant enzymes and enhance cellular defense mechanisms suggests a multifaceted approach to combat oxidative damage. This review also explores the pharmacological potential of Gulvel as a complementary therapeutic agent for oxidative stress-related conditions, discussing both in vitro and in vivo studies, along with the challenges in translating these findings to clinical applications. Overall, Gulvel’s antioxidant properties position it as a promising candidate for future research and therapeutic development in the realm of oxidative stress management.