NANOEMULGEL SYSTEMS: A COMPREHENSIVE REVIEW OF FORMULATION, MECHANISMS, AND APPLICATIONS
Rohith Menon*, Shripathy D. and Shabaraya A. R.
ABSTRACT
A new family of hybrid formulations known as nanoemulgels combines the advantages of gels and nanoemulsions to provide special benefits for drug delivery systems. These formulations, which offer superior stability, controlled release, and bioavailability for both hydrophobic and hydrophilic medicines, usually comprise nano-sized droplets distributed inside a gel matrix. Better penetration and targeted distribution, especially for topical treatments, are made possible by the thick consistency of gels and the small particle size and large surface area of nanoemulsions. In various kinds of therapeutic domains, such as dermatology, transdermal medication administration, and cosmetic formulations, nanoemulgels have demonstrated considerable potential. This review highlights the benefits of nanoemulgels over traditional systems by examining their formulation processes, characterisation methods, and possible uses. Future directions for improving their design and therapeutic efficacy are also covered, along with issues pertaining to their stability, scalability, and safety. In general, nanoemulgels offer a flexible foundation for cutting-edge drug delivery systems and represent an inventive method of improving the functionality of pharmaceutical and cosmetic products.
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