Abstract

Deepak Muthu S., Ayeesha Lubaba M., Nivedha V., Nithyapriya R., Sathiyabalan G.* and Bhuvaneshwari Santharam

ABSTRACT

Diabetic foot ulcers (DFUs) are a common complication of diabetes, leading to significant morbidity, mortality, and healthcare costs. Traditional medicine has utilized plants from the Fabaceae family to treat various ailments, including wounds and ulcers. This review aims to summarize the current evidence on the use of Fabaceae family plants in treating DFUs. A comprehensive literature search identified several Fabaceae plants with promising wound healing properties including Melilotus officinalis, Buteo monosperma, Prosopis farcta, Tephrosia purpurea, Astragalus propinquus, Cassia auriculata, Acacia catechu, Cicer arietinum, Vigna unguiculata, Phaseolus vulgaris, Prosoposis africana and Senna occidentali. These plants possess bioactive compounds with antimicrobial, anti-inflammatory and antioxidant properties, which may aid in wound healing and tissue repair. While the available evidence is promising, further clinical trials are necessary to fully elucidate the efficacy and safety of these plants in treating DFUs. This review highlights the potential of Fabaceae family plants as adjunct therapy for managing DFUs and emphasizes the need for continued research in this area.