LIPOSPHERES
Dr. C. Aparna*, Rithika Chilukuri
ABSTRACT
Lipospheres are novel lipid-based drug delivery systems developed to address the limitations of poorly water-soluble drugs, which frequently exhibit low bioavailability and inconsistent therapeutic response. They consist of a solid hydrophobic lipid core in which the active drug is dispersed or dissolved. They have been employed for the controlled delivery of a wide range of drugs, including anti-inflammatory medications, antibiotics, and anticancer agents, and as carriers for vaccines. This review emphasizes the formulation methods, advantages, limitations, and diverse applications of lipospheres, highlighting their potential as a simple, cost-effective, and versatile lipid-based carrier system in drug delivery.
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