Abstract

Dr. M. Siva Ganesh*, R. Divyalakshmi, S. Thilgavathi

ABSTRACT

The aim of the present study to evaluate the phytochemical screening, preparation of Anti-Dandruff shampoo from poly herbal formulation and its antioxidant, antimicrobial and anti-inflammatory activity of Aqueous extract of different parts of medicinal plants. The aim of the recent work was to develop the polyherbal antidandruff shampoo and evaluate the formulated shampoos for physical parameters. Shampoos are the products which are used for the removal of the surface grease and dirt from the hair scalp and shaft. The present study focused on the preparation of a polyherbal anti-dandruff shampoo using selected medicinal plants known for their beneficial effects on hair and scalp health. The plants used in this formulation included Azadirachta indica, Ocimum tenuiflorum, Eclipta prostrata, Phyllanthus emblica, Hibiscus rosa-sinensis, and Sapindus mukorossi. These plants were selected based on their traditional use in herbal medicine and their reported biological activities such as antimicrobial, antioxidant, and anti-inflammatory properties. Several evaluation tests were performed to assess the quality and effectiveness of the prepared herbal shampoo. The preliminary photochemical screening showed that the most of the secondary metabolites mainly found in aqueous extract of polyherbal formulation. Especially bioactive compounds such as Alkaloids, Flavonoids, Phenols, Saponin and Tannin were highly present in the aqueous extract when compared to other solvents like Chloroform, Ethyl acetate, Petroleum ether and Aqueous extract based on the solubility. The physicochemical properties of the shampoo, such as pH and foam stability, were determined. The pH of the shampoo was found to be within a range that is compatible with the natural pH of the scalp. Maintaining an appropriate pH is important for preventing scalp irritation and maintaining hair health. The results indicated that the polyherbal formulation possessed significant antioxidant activity due to the higher free radical scavenging activity which may help protect scalp tissues from oxidative stress and support healthy hair growth. Antimicrobial activity was another important parameter evaluated in the study. The antimicrobial assay study revealed that the aqueous extract of different part of polyherbal shampoo showed potential antibacterial activity against Staphylococcus, Streptococcus pyogens species were selected viz., bacterial cultures in a maximum concentration based on concentration dependent manner and also antifungal activity against candida albicans. The plant extracts used in the formulation are known to possess natural antimicrobial compounds that inhibit the growth of microorganisms responsible for scalp infections and dandruff. The results suggested that the polyherbal shampoo formulation exhibited antimicrobial activity, which contributes to its anti-dandruff effect. The outcome of the present studies revealed that polyherbal shampoos can be prepared easily from the natural plant sources having antimicrobial properties and herbal antidandruff shampoos are better alternatives than synthetic shampoos.