ASSOCIATION OF VITAMIN D3 DEFICIENCY IN NONALCOHOLIC LIVER DISEASE
Ibtihal Hashim Azeez*
ABSTRACT
The crucial secosteroid hormone Vitamin D has an influence on the homeostasis of calcium, however, in the recent years, there have been growing idea that this vitamin also contributes to cell differentiations and proliferations, and it acts as an anti-inflammatory and immunomodulatory factor. Deficiency of Vitamin D is commonly stated in several causes of chronic hepatic diseases and is related to evolution and development of the non-alcoholic fatty liver diseases (NAFLDs) and in infection with chronic hepatitis C (CHC). The roles of Vit. D in the pathogenicity of CHC and NAFLD have not entirely recognized, but it appears that, Vit. D’s contribution to the regulations and activations of the adaptive and innate immune responses as well as its anti-proliferative effects can clarify its significance in such hepatic diseases. Available studies indicated performing routine testing for hypovitaminosis D in hepatic disease patients. For this study, we did in methodology some tests that associated with NAFLD to identify effecting biomarker such as Liver Function tests and Lipid profile tests and Diabetes profile test. Further prospective studies demonstrating the impact of vitamin D replacement in NAFLD is required. Aim of study to identify effecting of deficiency Vit D3 for nonalcoholic liver disease.
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