Abstract

Subhashitha S.*, Heeba Fatima, Kadeeja Nuhi, Khadeeja Shifa, Mubeena

ABSTRACT

Hyperhidrosis is a condition characterized by excessive sweating that affects human beings. Antiperspirants are the first-line treatments for hyperhidrosis. Antiperspirants help reduce excessive sweating. This study was conducted to to investigate home remedies to overcome body odor, and to develop and evaluate herbal antiperspirant. When an antiperspirant is applied to the skin surface, its Active ingredients i.e., aluminium chlorohydrate gets dissolved in the sweat or moisture present on the skin surface of armpit, the dissolved substance forms a gel creates a small temporary ‘plug’ near the top of the sweat gland, which considerably reduces the amount of sweat producing from the skin surface. In this study the formulated Antiperspirant roll-on of F1-F4 incorporates active ingredients, such as Aluminium chlorohydrate including chemical with Bees wax, Stearic acid, Liquid Paraffin, Span 20, Tween 80, Glycerol disodium EDTA, Sodium benzoate and orange oil utilized as the excipients. The formulated Antiperspirant roll-on was analysed for its various evaluation test. Among the overall formulation of F1-F4 prepared, F4 formulation was chosen as optimum formulation as it shows good antibacterial activity while performing antibacterial activity by agar well diffusion method using gram negative bacteria Escherichia coli on nutrient agar medium incubated for 24hrs against standard gentamycin. The result confirms that the Antiperspirant roll-on using Moringa oleifera possessed desirable antibacterial activity making it suitable for application.