Abstract

Shreya Sonak, Sagar Trivedi*, Kamlesh Wadher, Milind Umekar

ABSTRACT

Chocolate is highly sophisticated and infinitely a versatile food that can be combined to create completely different taste and sensations. The objective of the present research work is to develop a palatable chocolate formulation of Montelukast for paediatric administration and to increase patient compliance. In present investigation the medicated chocolates were prepared by two methods using cocoa powder, cocoa butter, lecithin, powdered sugar and using compound chocolate base. Lecithin used during formulation increased the hardness of chocolate.The prepared medicated chocolate were characterized for physical characteristics, drug content and in vitro drug release. Study indicated that both the methods used in the formulation had similar drug release pattern. Batch F4 showed 95.07% at 30 mins whereas F5 showed 93.55% at 30 mins. The formulated chocolate was slightly bitter in taste but is a convenient form of dosage form for paediatrics.