Abstract

I. Sudha Rani*, Y. Anil Kumar, K. Ravi Kumar, A. Prathyusha and K. Indira

ABSTRACT

Obesity is directly linked with cardiovascular diseases. Fenugreek significantly decreases the body weights because it?s having the main chemical constituents of quercitin, 4.hydroxyisoluecine, fenugrin, trogonelline these are decreases the lipids and cardiac marker enzymes. Flavonoids, alkaloids present in the plant extract proved to have a protective effect against the fructose induced diabetic and hyperlipidemia in animals by a significant decrease in the blood glucose levels. In the present study it shows the prolonged use of fructose high diet to the animals lead to the tissue damage (pancreas), increase in the nonfunctional pancreatic cells shows that the fructose affected the pancreas from its function. Diabetes is associated with hyperlipidemia. A reduction in serum lipids, particularly of the LDL and VLDL fraction and triglycerides, should be considered as being beneficial for the long term prognosis of the patient. In the present study LDL and VLDL levels increased and the HDL levels decreased after the 28 days treatment.