Abstract

Ekenna I. C. and Afieroho O. E.*

ABSTRACT

Friedelane-type isoprenoids are naturally occurring pentacyclic triterpenes that includes friedelin and its derivatives. Several reports on their numerous biological activities in both in vivo and in vitro experimental models have been reported. This report is a review on the pesticidal friedelane-type isoprenoids of botanic origin, their mechanisms of action and salient structure activity relationship. Generally, the type and stereochemistry of the substituent at position C-3 of the friedelane 1 triterpene skeleton greatly affects biological activity of these phyto-constituents.