Abstract

*Kerenhappuch Isaac Umaru and Madu Sharif

ABSTRACT

Introduction: Glycemic control through diet is necessary for preventing or limiting the consequences of diabetes mellitus. Therefore, the consumption of functional foods and nutraceutical or bioactive compounds derived from plants used as food can be used as nutritional tools because of their clinical effects. Thus, Moringa oleifera is a vegetable plant protein with bio-active multipurpose, it has been used as a food source and for traditional medicine purposes due to possible antihyperglycemic properties. These properties may be explained by the presence of numerous phytochemicals in the seeds. The aim of this study was to determine the bioactive potential of Moringa oliefera seed on glycemic index on healthy albino rats. Materials and methods: The seeds of Moringa oleifera were collected in Maiduguri, Borno State Nigeria and the rats weighing 110-120g were procured from Faculty of Pharmacy Animal farm. The seed was dried and grinded into powder using pestle and mortar. The milk like powder was weighed and stored in an airtight container. The animals were acclimatization and randomly divided into Four groups of three animals per group, with one group serving as control. They were weighed and fasted for twelve (12) hours (overnight) before diet administration. Result: The Postprandial glucose Level of rats treated with Moringa oleifera formulated diet indicated significantly result with p