Abstract

A. Valankanni*, T. Sekar, P. Gurusaravanan and S. Sujatha

ABSTRACT

Objective: In the present study, antioxidant activities flower and fruit of the pet-ether, chloroform, acetone and methanolic extracts from Cadaba fruticosa (L.). Flower and fruit were investigated by employing established in-vitro studies. C. fruticosa is one of the folk herbal used in various traditional medicaments. Many people of rural and urban areas depend upon treatment, which has been developed through prolonged traditional experience. Method: The ability of the plant extract to act as hydrogen/electrons donor or scavenger of radicals were determined by in-vitro antioxidant assays using 2,2-diphenyl-2-picryl-hydrazyl free radical (DPPH.) scavenging, reducing power assay, superoxide radical (O2*-) scavenging activity, phosphomolybdenum assay, FRAP and metal chelating activity ,were performed to know the antioxidant potency of the plant extract of flower and fruit of C. fruticosa. Result: Results are evaluate higher in flower and fruit of C. fruticosa recorded antioxidant as well as to phytochemical quantitative of total phenol and flavonoid present in the plant extracts of C. fruticosa. The plant C. fruticosa methanolic extract of flower showed greater IC50 for DPPH assay (11.23?g/ml) and compare to other extract, higher Reducing power activity flower in methanol (1.296 ascorbic acid /100g extract), better fruit in phosphomolybdenum reduction (104.6mg/g extract) and higher superoxide radical scavenging activity in fruit extract (92.06%). However, the better metal chelating ability was shown by the water extracts of flower (9.11 Ascorbic acid /100g) compared to other solvent extracts. Conclusion: The result indicates the antioxidant and total phenol activity potential of C. fruticosa.