International Journal Of Modern
Pharmaceutical Research

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An International Peer Reviewed Journal for Science & Pharmacy Professional

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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Abstract

ANTIMICROBIAL POTENTIAL OF ENDOPHYTIC FUNGI ISOLATED FROM LEAF SAMPLES OF THE MEDICINAL PLANTS, ABUTILON INDICUM L. AND ACMELLA OLERACEA L.

Rajalakshmi P., *Nayak B. K., Ramkumar R. and Nanda A.

ABSTRACT

During the study period, endophytic fungi were isolated from leaf samples of two medicinal plants, Abutilon indicum L. and Acmella oleracea L. collected from our college APJ Abdul Kalam Eco-garden. The isolated fungi were subjected to antimicrobial analysis by active agar plug method in order to find their potency against pathogenic MTCC bacterial and fungal strains procured from IMTECH, Chandigarh, India. There are three endophytic fungi viz., Aspergillus niger, Cladosporium herbarum and Fusarium sp. were isolated from the medicinal plant, Abutilon indicum and two fungi i.e., Aspergillus japonicus and Trichoderma viride from Acmella oleracea L. Pathogenic bacteria i.e., Klebsiella pneumoniae and Bordetella pertussis were found to be more susceptible towards five endophytic fungi followed by other bacteria and Candida albicans. Escherichia coli and Candida albicans were found to be least affected by the fungal extracts. Pseudomonas aeruginosa was documented as average susceptible pathogenic bacteria among all. Active agar plugs of endophytic fungus, Aspergillus niger was recorded as a good inhibitor of microbial growth of both bacteria and Candida albicans in vitro comparison to other endophytes.

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