International Journal Of Modern
Pharmaceutical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Science & Pharmacy Professional

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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ISSN 2319-5878
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Abstract

PREVALENCE AND PREDICTORS OF ADVERSE DRUG REACTIONS AMONG HIV POSITIVE PATIENTS RECEIVING ANTIRETROVIRAL THERAPY AT A TERTIARY TEACHING HOSPITAL IN FREETOWN, SIERRA LEONE

Onome T. Abiri,* Diane A. Kawa, James P. Komeh, Sulaiman Lakoh, Alren O. Vandy, Abdul J. Njai, Gibrilla F. Deen, Zikan Koroma, James B.W. Russell, Samuel Massacquoi, Abdulai J. Bah, Richard M. Conteh, Thomas A. Conteh, Fawzi Thomas, Joseph S. K

ABSTRACT

ABSTRACT Background: Despite the benefits of Antiretroviral therapy (ART) in reducing morbidity and mortality related to Human Immunodeficiency Virus (HIV) infection, it is associated with adverse drug reactions (ADRs). This study was therefore conducted to assess the nature, prevalence, and severity of ADRs in HIV positive patients receiving ART since no such data is available in Sierra Leone. Methods: A cross-sectional descriptive study was conducted by interviewing and reviewing medical charts of 384 HIV-positive patients receiving ART at Connaught hospital in Freetown Sierra Leone. Information on socio-demographic characteristics of patients, details of medicines used, and adverse effects were collected and assessed. Binary logistic regression was used to determine the associations of the dependent variable with a 95% confidence interval and P-value

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