Abstract

Anirban Roy Chowdhury*, Sudipa Chakravarty and Amit Chakravarty

ABSTRACT

Resveratrol (3,4',5-trihydroxystilbene) belongs to a class of polyphenolic compounds called stilbenes. It may have numerous protective effects against age-related disorders, including renal diseases, through the activation of SIRT1. SIRT1 and NAD+-dependent deacetylase was identified as one of the molecules through which calorie restriction extends the lifespan or delays age-related diseases, and this protein may regulate multiple cellular functions, including apoptosis, mitochondrial biogenesis, inflammation, glucose/lipid metabolism, autophagy, and adaptations to cellular stress, through the deacetylation of target proteins. In our present study we observed the administration of trans-resveratrol might effect the blood parameters, LFT, RFT and the Body weight and height evaluation according to their age of different male and female thalassaemic patients. This study we conclude that trans-resveratrol play an important role to increase the blood parameters of both Beta and Hb E- Beta thalassaemic patients. It also very effective for the liver and kidney and it play very important role in body growth.