Abstract

Abdulhakim Umar Toro and Maya Datt Joshi*

ABSTRACT

Cancer is a disease characterized by uncontrolled proliferation of body cells. Hepatocellular carcinoma (HCC) is one of the most common malignant tumors worldwide. There are many treatment strategies available for hepatocellular carcinoma but there are several limitations of traditional surgery and radiation therapy and chemotherapy that results into failure and poor prognosis. In recent years, the development and advances of nanotechnology has brought new hope for the diagnosis and treatment of HCC. This article reviews the development of nanoparticles used for detection, diagnosis and treatment of hepatocellular carcinoma due to their large specific surface area and unique optical, electronic and magnetic properties. Moreover, research have shown that after Nanoparticle based therapy including nano-carriers can achieve active targeting effect, which improves the efficacy of chemotherapeutic drugs and decreases their side effects.