Abstract

Meera Ingale*, Rahul Kasliwal and Yogesh Gholse

ABSTRACT

Proniosomes are one of the novel provesicular drug delivery systems which are dry formulations coated with carrier such as non-iconic surfactants. Proniosomes are formulated in such a manner that they can overcome the drawbacks of niosomes such as physical instabilities, fusion and aggregation. Proniosomes can be administered by various routes like oral, intravenous, buccal, topical, transdermal, ocular etc. Proniosomes are liquid crystalline compact niosome hybrids which upon hydration form niosomes. They help in reducing physical stability problems involved with niosomes such as leaking, fusion, aggregation and provide convenience in dosing, distribution, transportation and storage showing improved results than conventional niosomes.