Abstract

Sunil Singh*, Anjana Sharma and Amarjeet Singh

ABSTRACT

Diabetes is contemplated as one of the most common chronic diseases internationally. It is an extensive pancreatic disease affecting large amount of the community globally. This is growing authentication that grows manufacturing and/or unsuccessful scavenging of ROS (Reactive Oxygen Species) may play a censorious part in chronic diseases. Lipid can be produced by peroxidation highly responsive ROS which control the chemical changes in close to all cellular integrant, leading to production of ROS and disorder in antioxidant protect system in diabetic thing has been reported. The antioxidants are used to treat and decrease the complications (diabetic retinopathy, diabetic nephropathy, diabetic neuropathy, myocardial infarction, and atherosclerosis) of diabetes mellitus. Herbal medications have been used for the treatment of variety of ailments among which Ficus religiosa belonging to the family Moraceae is the vital one. As mentioned in the herbal medicine system, F. religiosa have the potential to treat disorders including hyperglycemia, diarrhea, inflammatory disorders, epilepsy, and stomach problems, sexual and infectious diseases. There are countless studies on the reaction of antioxidants in the modulation of diabetes. The aim of this study was to abstract the middle role of oxidative stress in the pathogenesis of diabetes and the approaching role of antioxidants to overcome lipid peroxidation through their free radicals clearance properties.