A COMPREHENSIVE REVIEW ON EMULGEL: A NEW APPROACH FOR ENHANCED TOPICAL DRUG DELIVERY
Rani J. Rode*, Gouri R. Dixit, Kanchan P. Upadhye, Suparna S. Bakhle and Rohit T. Durge
ABSTRACT
Emulgel is a new approach and recent technology of NDDS for topical drug transport having characteristics of dual controlled release i.e emulsion and gel Emulsion used for treating for muscle pain, headache, acne, psoriasis, rheumatoid arthritis. When emulsion and gel used in combination its known as Emulgel. Emulgel is transparent gel which is used in pharmaceutical and cosmetic product. Emulgel overcome the problem which is come in gel and emulsion. Gel is a new class of formulation, gel release drug faster in comparison of ointment, cream, lotion etc. Limitation of gel in the delivery of hydrophobic drug through the skin. Overcome the limitation on emulsion based approach is being used so that even a hydrophobic therapeutic moiety can exhibit the unique properties of gels. Emulgel is prepared by different polymers which act as an emulsifying agent and thickening agent because the gelling capacity of these polymers give rise to stable emulsions by decreasing interfacial and surface tension while at the same time increasing the viscosity of the aqueous phase. Emulgel are having major advantages on novel vesicular systems as well as on conventional systems considering various aspects. The emulgel provide several favourable properties for its dermatological use such as greaseless, thixotropic, easily spreadable, emollient, easily removable, non-staining, water soluble, longer shelf life, transparent, bio-friendly and pleasing appearance.
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