International Journal Of Modern
Pharmaceutical Research

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An International Peer Reviewed Journal for Science & Pharmacy Professional

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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ISSN 2319-5878
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Abstract

PREPARATION AND EVALUATION OF ALLAMANDA CATHARATICA LOADED EMULGEL

Vikas Srivastav*, Swarnima Pandey and Dr. Amresh Gupta

ABSTRACT

The objective of the present work was formulation of emulsion containing allamanda cathartica in a gel topical delivery system(emulgel) for management of wound. Crude extract of Allamanda Cathartica leaves were subjected to various chemical test for the identification of different active phytoconstituents. The ethanolic extract shows the presence of tannin, Phlobatannin and saponin. Emulgel was prepared and different concentration of HPMC and propylene glycol were used. six batches were prepared with 1% concentration of gelling agent. Out of six batches (F1, F2, F3, F4, F5, F6) F5 showed good spreadibility and drug release in comparison with other batches. The selected batch was of greenish colour, semisolid consistency, neutral pH and without any grittiness. Spreadibility and in vitro release were found to be 17.20 cm and 79.40%.

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