Abstract

UV SPECTROSCOPIC ESTIMATION OF LEVOSULPIRIDE IN BULK DRUG AND FORMULATIONS

ABSTRACT

A simple and sensitive uv spectrophotometric method has been developed for the estimation of Levosulpiride in tablet dosage form was described. From the solubility data phosphate buffer (pH 8) was used as solvent and shows absorption maximum at 291 nm. The Beer’s Law range is 10-100 ?g/ml. The linear regression for method found to be 0.999. When tablet dosage forms where analyzed, the results obtained by the proposed methods are in good agreement with the labelled amount and the developed method was validated statistically as per ICH guidelines. Conclusion: The developed method is simple, sensitive, specific and can be successfully employed in routine analysis of Levosulpiride Pharmaceutical dosage forms.