International Journal Of Modern
Pharmaceutical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Science & Pharmacy Professional

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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ISSN 2319-5878
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Abstract

DOCKING STUDY OF FDA-APPROVED DRUGS AND MODIFIED DERIVATIVES ON HUMAN CORONAVIRUS PAPAIN-LIKE PROTEASES (4OVZ)

Vidya Magar*, Chandrakant Gawli, Prasad Dahatonde, Rushikesh Dhondge, Hanuman Gholap and
Mohini Gopal

ABSTRACT

The COVID-19 outbreak is a matter of concern worldwide due to unavailability of promising treatment comprising medication or vaccination till date. The discovery of antiviral drug is of immense importance in the existing spread of novel coronavirus. The goal of the present study was to evolve an opposite antiviral drug against the novel COVID-19 virus. A directly succeeding perspective would be to use the prevailing influential drugs from several antimicrobial and chemotherapeutic agents. The encouraging approach is to identify promising drug molecules and compounds through virtual screening via molecular docking of FDA-approved drugs and some derivatives for probable therapeutic outcome.

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