International Journal Of Modern
Pharmaceutical Research

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Abstract

COMPARATIVE PHARMACEUTICO-ANALYTICAL STUDY OF SELF PREPARED BOLA PARPATI AND MARKET SAMPLE OF BOLA PARPATI

Dr. Monish Maruti Shinde*, Dr. Sushma Lodhe, Dr. Swati Adhave and Dr. Sharadkumar Maurya

ABSTRACT

Introduction: Parpati means thin flakes. It is first described in 8th century by Acharya Nagarjuna in kushtaroga for external use. But later in 11th century Acharya Chakrapani (commentator of Charaksamhita) described parpati kalpana in Grahani chikitsa for internal use. Now a day’s raktapradara, raktaguda, raktarsha diseases are common health problems and sometimes ignorance towards these disorders causes life threatening effects. Effective choices are available for the treatment of these common disorders but it is a need to be more potent and cost effective formulations which show fast results and more therapeutic effect. In Ayurveda acharya mentioned various effective drugs on above diseases such as bolabaddha rasa, bola churna, bola parpati etc. The bola parpati contains kajjali and bola having the properties of constricts the blood vessels and leads to coagulation which helps to stop bleeding and kajjali act as catalyst which enhances the properties of bola. Demand of ayurvedic medicine is increasing day by day. So, it is necessary to provide potent medicine with quality assured by rasagrantha. Rasashastra has mentioned organoleptic tests and kalpasiddhi lakshana for every formulation. Siddhi lakshana of parpati Kalpana and its organoleptic tests are also mentioned in text. Few ayurvedic pharmacies prepare bola parpati. Before sample being available in market, pharma companies do analysis for quality assurance. Neither this analysis is exposed to anyone nor it printed on sample. Therefore, we choose to compare our preparation with market sample to establish some analytical parameters for bola parpati which will be useful for further studies. Aim: To compare the pharmaceutico-analytical properties of self- prepared bola parpati with market sample. Material and Methods: Parada shodhana was done according to Rasatarangini and Gandhaka shodhana was done according to Ayurved Prakash. Kajjali was prepared from Shodhit parada and Shodhit gandhaka. Bola parpati was prepared according to Yogaratnakara. The prepared Bola parpati was then subjected to analytical tests alongwith the market sample of Bola parpati. The pharmaceutico-analytical properties of self-prepared Bola parpati and market sample were compared to draw the conclusions. Observations: The pharmaceutical observations during Parada shodhana, Gandhaka shodhana and bola parpati preparation were noted. Also, the analytical observations of both self-prepared and market sample of Bola parpati were noted and compared. Conclusions: The results showed a slight difference in the pharmaceutico-analytical properties of self-prepared and market samples of Bola parpati. There is however a need of Pre-clinical and clinical studies of Bola parpati to study its efficacy.

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