Abstract

Umadevi D., *Nayak B. K., Angelin Buela Caroline M., Nithiya G. and Anima Nanda

ABSTRACT

Multi drug resistance among pathogenic bacteria is the key problem and also challengeable for every microbiologist in order to find out novel antibiotics to overcome this situation. Therefore, our present research work is aimed to catch better antimicrobial compounds from unique soil actinomycetes isolated from dissimilar environment i.e., Fire Ant hill soil. During the study period, a total of 43 isolates of actinomycetes were isolated from the fire ant hill soil samples of Dr. APJ Abdul Kalam Eco garden of our KMGIPSR campus, Puducherry. Among the 43 isolates, 25 isolates produced pigments on the PDA media. All the isolates were subjected to anti-bacterial and anti-candida activity. Among the actinomycetes, isolates like A6, A8, A31, A33 and A35 showed good antimicrobial activities against the MTCC cultures viz., Vibrio cholera (MTCC-3906), S. epidermidis (MTCC-435), Bacillus subtilis (MTCC- 1755), Pseudomonas aeruginosa (MTCC-424), Candida albicans (MTCC- 439). 12% of all the actinomycetes isolates showed good antimicrobial activity against all the bacteria and Candida albicans while 46% showed the least activity with pigmentation but 42% were not able to show any pigmentation during their growth on different media on laboratory conditions.