International Journal Of Modern
Pharmaceutical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Science & Pharmacy Professional

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

INTERNATIONAL JOURNAL OF MODERN PHARMACEUTICAL RESEARCH has been indexed and abstracted by various international reputed agencies like : Google Scholar , Index Copernicus , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , Cosmos Impact Factor , Scientific Indexing Services (SIS) , Web of Science Group (Under Process) , IFSIJ Measure of Journal Quality , International Scientific Indexing, UAE (ISI) (Under Process) , IP Indexing (IP Value 2.42) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing (ISI) , Scope Database , ABCD Index , Academia  and many more.
ISSN 2319-5878
IMPACT FACTOR: 6.669

Abstract

FORMULATION AND EVALUATION OF PIROXICAM EMULGEL USING PERMEATION ENHANCERS FOR TOPICAL DELIVERY

*Poonam Yadav, Durga Pandey, Praveen Tahilani and R. B. Goswami

ABSTRACT

The objective of this work was to prepare and evaluate emulgel of Piroxicam which will increase skin penetration of drug due to penetration enhancers in comparison with marketed preparations of the drug. Droplet’s size of emulsion was found 759 ?m. The drug content found to be 98.1 in the gel and viscosity 20211 ± 0.43 cP spreadibilty of formulation was more than marketed formulation. Optimized formulation showed 83.1 % release in 8 hours which is little more than marketed preparation. Emulgel are more comfortable than cream and ointments. Materials selected for preparation are biocompatible in nature. Piroxicam will be highly effective drug in the treatment pain, swelling, and joint stiffness from arthritis. Its analgesic activity can be improved by adding methyl salicylate, mentha oil and clove oil in the formulation. Mentha oil and clove oil used for permeation enhancers in the formulation for better drug absorption. More drug will be absorbed by emulgel than conventional formulation and reduces dosing frequency. We can conclude that Piroxicam is more effective when entrap as microemulsion and given in emulgel form as compared to conventional dosage form of the same drug.

[Full Text Article] [Certificate Download]

Indexing

News

  • Call for Paper

    IJMPR  Invited to submit your valuable manuscripts for Coming Issue.

  • IJMPR: MAY ISSUE PUBLISHED

    MAY 2024 Issue has been successfully launched IJMPR on 1 MAY 2024.

  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.

    .

  • IJMPR: New Impact Factor

    IJMPR Impact Factor has been Increased to 6.669 for Year 2024.

  • NEW ISSUE PUBLISHED

    Its Our pleasure to inform you that, IJMPR 1 May 2023 Issue has been Published, Kindly check it on https://ijmpronline.com/current-issues

Best Paper Awards

IJMPR is awarding one article from each issue as "BEST PAPER AWARD", Winner will get a "Certificate of Appreciation" along with cash reward. The best paper of the issue is as follows :

Best Article of current issue

Download Article : Click here

Powered By IJMPR | All Right Reserved

IJMPR