Abstract

Prapti S. Jadhav*, Pratima M. Khichade, Sushil S. Kore, Mayuri J. Chandrawanshi, Suraj G. Malpani and Vishweshwar M. Dharashive

ABSTRACT

Polycystic ovary syndrome (PCOS) is one of the most common endocrine and metabolic disorders in premenopausal females. PCOS is heterogenous in nature, defined by a combination of hyperandrogenism and signs of ovarian dysfunction and the syndrome, with no other specific diagnosis. The pathophysiological aspect of PCOS focuses primarily on hyperandrogenism, which leads to hormonal dysfunction, insulin resistance, and impaired follicular formation. With risk of associated comorbidities such as endometrial cancer and type II diabetes. This review summarizes the most relevant and up-to-date reports on PCOS, briefly address the pathophysiology of the disease, and then detail its diagnostic criteria. Throughout the review, we highlight the complexity of PCOS in terms of pathophysiology, diagnosis, and the required interdisciplinary therapeutic approach.