SYNTHESIS AND ANTICANCER ACTIVITY OF SOME NOVEL 2-AMINO THIAZOLE DERIVATIVES
*Dr. Narendra Singh, Govindasamy Jeyabalan, Dr. Yogendra Singh
ABSTRACT
A series of 2-aminothiazoles derivatives have been synthesized and tested for their anticancer activity. All the synthesized novel compounds were screened for anticancer activity. It was also found that compounds NS1 , NS2, NS6 and NS8 showed very good anticancer activity whereas all the other compound have showed mild to moderate anticancer activity as compared to standard drug. Syntheses have been carried out following simple methodology in excellent isolated yields. The structure and purity of the original compounds were confirmed by IR, NMR, and elemental analysis. These preliminary results indicate that some of compounds are exhibiting good activity.
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