A REVIEW ARTICLE ON SOLID LIPID NANOPARTICLES
Saloni Manglik*, Chanda Ray, Dr. Amarjeet Singh and Jaya Singh
ABSTRACT
In recent years, there has been a lot of interest in solid lipid nanoparticles (SLNs), also known as lipid carriers, which have been the subject of a lot of research. Lipid nanoparticles have gained popularity due to the fact that they are generally considered to be non-toxic, biocompatible, and simple to manufacture formulations. Because they are biodegradable, nano-structured lipid carriers and SLNs are non-toxic to living organisms. Furthermore, they are extremely stable. Moreover, despite the fact that nano-structured lipid carriers and SLNs are based on lipids and surfactants, the effect of these two matrixes in the construction of excipients is also discussed, as is their pharmacological significance in novel drug delivery approaches, stability, and long-term preservation. The release mechanism of the drug as well as the various methods of preparation of solid lipid nanoparticles, as well as their advantages and disadvantages, are discussed in detail.
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