FORMULATION AND EVALUATION OF GLIPIZIDE ORAL ROUTE OF HYDROGEL
Dr. Jyoti Rai*, Pragati Pandey and Dr. J. Narayan Mishra
ABSTRACT
Guargum- Carbopol Hydrogel could be used to deliver micromolecular medications in a controlled manner, according to the researchers. Because of its oral and mucoadhesive properties, drug release can be targeted to the top region of the small intestine, minimizing uneven absorption of many micromolecules. It was also shown that in acidic environments, the extent of hydrogel swelling was reduced; hence, drugs that would break down in acidic stomach conditions could be protected from the harsh acidic environment.
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