Abstract

*Krunal Trivedi, Ankit Paliwal, Jayesh Dwivedi and Ayush Garg

ABSTRACT

Wounds have been defined as a disruption of cellular, anatomical, andfunctional continuity of a living tissue and healing is the interaction of a complex cascade. It may lead to the restoration of structural and functionalintegrity of strength of injured tissues. The present study shows the wound healing and ulcerogenic property of Kaempferia rotunda(Ginger). Kaempferia rotunda (Ginger) is a plant belonging to ginger family. China is native place and has a subcontinent to India. It is reportedly naturalized in Java, Malaysia and Costa Rica. Kaempferia rotunda (Ginger) plant has many medicinal uses in Ayurvedic and allopathic medicinal systems. this is also known as bhumichampa.In this study, evaluation of wound healing potential of the extract and rhizomes and tubers of K.rotunda(Ginger)and its effect influence wound toprovide a lessoedematous, less painful, adequate antioxidant effect for healing.Evaluate the wound healing potential of the ethanol extract andrhizomes and tubers of K.rotunda(Ginger)onsurgical wound healing using a rat full thickness excision wound model.The active extract or essential oil with faster wound healing effect wasfurther subjected forthe active extract or essential oil with faster wound healing effect was subjected to successive solvent extractions with waterimmiscible organic solvents of increasing polarities and the woundhealing potential of each fraction was then evaluated topically viaexcision wound healing model.evaluate safety of the extracts, essential oil and the fractionsafter single and repeated dose (28-day) administration in animal model for safe wound healingand anti-ulcerogenic.