Abstract

Anushree Jain*, Rubeena Khan, Rinki Vishwakarma, Sapna Choubey, Shayma Khan

ABSTRACT

Dendrimers are a new class of polymeric materials. Dendrimers are nano-sized, radially symmetric molecules with well-defined, homogeneous and monodisperse structure that has a typically symmetric core, an inner shell, and an outer shell. Their three traditional macromolecular architectural classes are broadly recognized to generate rather polydisperse products of different molecular weights. A variety of dendrimers exist, and each has biological properties such as polyvalency, self-assembling, electrostatic interactions, chemical stability, low cytotoxicity and solubility. Structural advantages allow dendrimers to play an important role in the fields of nanotechnology, pharmaceutical and medicinal chemistry. As a result of their unique behaviour dendrimers are suitable for a wide range of biomedical and industrial applications. The bioactive agents can be easily encapsulated into the interior of the dendrimers or chemically attached that is conjugated or physically adsorbed onto the dendrimer surface, serving the desired properties of the carrier to the specific needs of the active material and its therapeutic applications. The review aims to emphasize on construction, characterization, drug delivery and possible application of dendrimers in various areas of research, technology and treatment.