Abstract

Aadarsh Richhariya*, Nitendra Rohit and Dr. Yuvraj Singh Dangi

ABSTRACT

Transdermal drug delivery systems were introduced to address the issues with drug delivery, particularly via the oral route. A transdermal patch is an adhesive patch that is applied to the skin and contains medication that is intended to be absorbed through the skin and into the bloodstream. Bypassing the digestive system and the hepatic first-pass effect, transdermal patches deliver drugs directly into the circulatory system. The greatest challenge with transdermal drug delivery is the barrier nature of skin, which is provided by its outer layer, that is, the stratum corneum (SC). This barrier limits the number of drugs, which are capable of being administered via these routes. Pharmaceutical preparations known as transdermal patches come in a variety of sizes and contain one or more active ingredients that are circulated throughout the body. When used as a formulation method to improve drug administration through topical channels, TDDS technology is successfully capturing significant market value for biomedical applications in the pharmaceutical industry, which is growing significantly.The review provides insightful information about the transdermal patch, including its benefits and drawbacks,anatomy of skin in relation to TDDS ,mode of action, different types , basic factors that affect them , methods of evaluation, and modes of application and future prospective.