Abstract

Prakhar Nema*, Alok Lodhi, Aman Chourasiya, Anil Chourasiya, Ankit Sahu, Sameeksha Jain and Arpana Purohit

ABSTRACT

Acne vulgaris affects about 85% of teenagers and may continue to adulthood. There are about two million visits to physicians per year for teenagers and the direct cost of acne treatment in the US exceeds $1 billion per year. Acne is a cutaneous pleomorphic disorder of the pilosebaceous unit involving abnormalities in sebum production and is characterized by both inflammatory (papules, pustules and nodules) and no inflammatory (comedones, open and closed) lesions. Propionibacterium acnes and Staphylococcus epidermidis are common pus-forming microbes responsible for the development of various forms of, acne vulgaris. Common therapies that are used for the treatment of acne include topical, systemic, hormonal, herbal and combination therapy. It is the sequelae of the disease that are the distinguishing characteristics of acne in skin of color, namely post inflammatory hyper pigmentation and keloidal or hypertrophic scarring. Although the medical and surgical treatment options are the same, it is these features that should be kept in mind when designing a treatment regimen for acne. This review focuses on the treatment of acne using various drug delivery systems. Many herbal drugs are used for the treatment of acne vulgaris. Though they have very few numbers of clinical trials, many successful results have been recorded. There are many types of herbal drugs which act against acne vulgaris and some of those are:- Aloe Vera, Amaranth, Arnica, Asparagus, Barberry, Basil, Birch, Bittersweet nightshade, Brewer’s yeast, Burdock, Calendula, Celandine, Chaste tree, Chaste berry, Coriander, Cur cumin, Green Tea, Guggul, Jojoba oil, Kali bromatum, Labrador tea, Lavender, Liquorice, Mint, Neem, Orange peel, Pine, Poplan, Rhubarb, Rose, Saw palmuto, Soapwart, Stinging nettle, Tea tree oil, Thyme, Turmeric, Usnea Barbara, Viola, Walnut, Willow bark.