Abstract

Neerajkumar Sharma Manohar, Senorita Pukhrambam, Anuradha Maibam, Kabita Laishram and *Oinam Joychandra Singh

ABSTRACT

Introduction: Antibiotics are crucial in management of various forms of infections so as to decrease morbidity and mortality. Objective: The aim of this study is to analyse the prescribing pattern of antibiotics among the surgical in-patients on the basis of the WHO AWaRe classification. Method: Data was collected from 525 case sheets of the surgical in-patients for a period of 1 year. Collected data included age, sex, diagnosis, name of antibiotics, co-prescribed drugs, route of administration, duration of treatment, adverse drug reactions/ events and duration of hospital stay which was entered in a pre-designed form. Descriptive statistics was used for analysis of the data. Results: 22.3% antibiotics was used in the age group of 31-40 years as single drug (51.4%) given via intravenous route (92%) with the most common class being Cephalosporins (34.4%). ACCESS group comprised of 59.28% of antibiotics in total with the average duration of stay being 3.8 days. Discussion: WHO has developed the WHO AWaRe classification to decrease the problem of antimicrobial resistance going hand-in-hand with the Antibiotic Stewardship Program. Cephalosporins accounted for the major class of drug use with Ceftriaxone alone used with 34.4%. ACCESS group of the AWaRe classification comprised of 59.28% of the total antibiotic use in the study with the average duration of stay of the patients being 3.8 days. Conclusion: Differential diagnosis for as to spill out why physicians do not follow guidelines and WHO approach towards improving prescription pattern needs utmost attention and intervention so as to improve the quality of life of the patients thereby decreasing patient morbidity and mortality.