International Journal Of Modern
Pharmaceutical Research

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Abstract

TO STUDY THE EFFECT OF COMBINATION THERAPY OF MANJISTHA, HARIDRA AND DARUHARIDRA ON PSORIASIS (EK KUSTHA)

*Dr. Preeti Bhatt Joshi, Dr. Dinesh Joshi and Prof. Dr. Swapnil Singhai

ABSTRACT

Psoriasis is one of the most common dermatologic disorder and a chronic skin disorder of present day. Though this disorder is not a contagious but it is often source of social embarrassment. Patients often isolate themselves from the fear of rejection from the society. Psoriasis is marked by periodic flare-ups of sharply defined red patches, covered by a silvery, flaky surface. In Ayurveda almost all skin disorders brought under one term i.e Kushta. Under this one variety of Kshudra Kushta is Eka Kushta whose signs and symptoms co-inside with that of Psoriasis. Aswedana, Mahavastu, Mastya Shakalopama are the feature mentioned by Acharyas for Ek-kushta. In Psoriasis relapsing nature is most common, which suggests that it needs long term treatment. The research study is performed with some herbal drugs and their effects were evaluated with the help of clinical study. Total 30 patients diagnosed as Ek-kustha (Psoriasis) of any socio-economic status, age group of 15-65 years and irrespective of sex of all ethnic origins were randomly selected. The drug Manjistha, Haridra and Daruharidra Lepa was applied for 6 months. Assessment was done on subjective parameters and obtained data was analyzed using appropriated statistical tests and conclusion was drawn that the combination therapy is highly significant in cases of Ek-kustha (Psoriasis). The combination therapy provided a significant effect on the sign and symptom Aswedanam (68.18%), Matsyashaklopamam (73.23%), Krushnac-aruna varna (66.67%), Kandu (71.79%), Rukshata (66.67%), Mandala (75%) and Bahaltva (72.22%). In symptom Mahavastum 68.75%, Sraava 66.67% and Daha 62.50% effect was observed. Most of the patients that are 22 patients (73.34%) were showed moderate response, followed by 4 patients (13.33%) were got marked relief, 1 patient (10%) has showed mild improvement and 3 patients (10%) were completely cured after completion of the treatment.

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