ROLE OF ASPIRIN IN DIABETES MELLITUS PATIENTS: A REVIEW
Dr. Divya Amaravadi*, Sindhuja Mekala, Jyothi Thummala, Srihari Avusherla, Dr. Rama Rao Tadikonda
ABSTRACT
Diabetes is one of the most common non-communicable diseases worldwide. India suffers from rising prevalence in both urban and rural areas due to lack of public awareness of the disease, limited health facilities, high cost of treatment, suboptimal glycemic control and increased diabetic complications. It is observed that Diabetics are twice as likely to suffer cardiovascular events such as heart attack and stroke as per the American Diabetes Association. Type 1 Diabetes is more commonly seen to develop in childhood or adolescence whereas Type 2 Diabetes is seen to develop at any age. Type 2 diabetes is most common in people over the age of 40. However, the role of aspirin in primary prevention in patients without cardiovascular disease is controversial. As a secondary prevention medication, aspirin is effective in preventing cardiovascular events in patients with pre-existing cardiovascular disease. Indeed, in low risk patients, the modest benefit of reducing major vascular events may be offset by increased bleeding risks such as intracranial and gastrointestinal bleeding. Hence, Diabetes mellitus is seen to be associated with a significant increased risk of both primary and recurrent atherothrombotic events and thereby complicating aspirin therapy.
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