NANOSPONGE APPROACHES FOR ORAL DOSAGE FORM: A REVIEW
Mahesha Keerikkadu*, A. R. Shabaraya and Fmith Celvia Miranda
ABSTRACT
Targeted and regulated drug delivery for both topical and oral application is made possible by an inventive and evolving technology known as a nanosponge. In the pursuit of directing the drug to the required site of action, nanoparticle-based drug delivery systems, such as nanosponge delivery, are essential. The oral route is seen to be the most convenient for administering medications to patients. A designed product can be made utilizing nanosponges, which are built on nanoscale polymer spheres that can suspend or entrap drug substances. The major developments in the therapeutics area will be target-oriented drug administration advances in therapeutic efficacy. These tiny sponges can travel through the body to their designated target area, where they stick to the surface and begin to release the medication gradually and precisely. Nanosponge formulations involve encapsulation of drugs in a polymeric material and thus provide patient compliance, controlled site-specific drug release, increased formulation efficacy, improved stability and drug dosing. The drugs which have low solubility will be delivered to the site using the nanosponge formulations. With enhanced solubility and increased bioavailability, nanosponge tablets assist cure conditions like cancer, diabetes mellitus, inflammation, and more. This article deals with the general introduction to nanosponge and oral delivery of nanosponges, its formulation, characterization with the different applications of nanosponge tablets.
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